UNEXPECTED ISOLATION OF A NEWCASTLE DISEASE VIRUS

Isolation and pathogenicity identification of avian paramyxovirus serotype 1 (Newcastle disease) virus from a Japanese quail flock in Iran

Newcastle disease virus (NDV) was isolated and identified for the first time from a flock of Japanese quail suspected to ND in Iran. Birds of the flock aged variously, and some of them died from the disease. Loss of appetite, weakness and decrease in egg production, diarrhea and nervous symptoms were the main clinical signs in the birds. Hemorrhagic lesions of the intestinal tracts and proventr...

Replication of Newcastle Disease Virus

Infection of L cells with Newcastle disease virus (NDV) results in abortive replication, with the production of very few plaque-forming units (PFU) of virus per cell (W. C. Wilcox, Virology 9:30, 1959; K. Paucker et al., Virology 17:301, 1962). It is known that interferon is synthesized by L cells infected with NDV, and the possibility exists that this endogenously produced inhibitor may be res...

Efficacy of Thermostable Newcastle Disease Virus Strain I-2 in Broiler Chickens Challenged with Highly Virulent Newcastle Virus

Newcastle disease (ND) is a major threat to poultry industry production throughout developing countries. The Newcastle disease viruses (NDVs) infecting industrialized and indigenous poultry in Iran are velogenic strains and responsible for the frequent outbreaks of ND in poultry farms even in vaccinated flocks causing serious economic losses in the commercial and indigenous poultry. However, va...

A Comparative Study on Histopathologic Effects of Iranian Newcastle Disease Virus Isolates

Experimental Infection of Turkeys with A Virulent Newcastle Disease Virus Isolated from Broiler Chickens

Newcastle disease (ND) is a highly contagious infection of many avian species, mainly chickens and turkeys, with a devastating impact on worldwide poultry production. The ND accounts for heavy losses in Iranian poultry flocks. There are some reports regarding the epidemiology of this infection in Iran. This study was performed to investigate the infection of turkeys with a Newcastle disea...